AT/RT

Last modified by Hussein Abdallah on 2025/04/23 20:40

FACTS

#1 most common pediatric brain malignancy

  • malignant WHO IV embryonal tumor 
  • inactivation of SMARCB1 or SMARCA4

CONSULT

HPI 

usual presenting sx: HA, n/v, ataxia 

infants: irritability, lethargy, macrocrania

Drop mets ROS: back pain, urinary retention, leg weakness 

Associated with Fanconi Anemia

FOCUSED EXAM

 

IMG 

 

A/P

[ ] Counsel: this is a very poor prognosis tumor, careful delivery to patient and family under the right setting 

Classification

 

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Figure 1: Sea