AT/RT
Last modified by Hussein Abdallah on 2025/04/23 20:40
FACTS
#1 most common pediatric brain malignancy
- malignant WHO IV embryonal tumor
- inactivation of SMARCB1 or SMARCA4
CONSULT
HPIusual presenting sx: HA, n/v, ataxia infants: irritability, lethargy, macrocrania Drop mets ROS: back pain, urinary retention, leg weakness Associated with Fanconi Anemia |
FOCUSED EXAM
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IMG
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A/P[ ] Counsel: this is a very poor prognosis tumor, careful delivery to patient and family under the right setting |
Classification
Figure 1: Sea