MRI/LP Drugs

Last modified by Hussein Abdallah on 2025/04/19 20:36

Drugs for LP

Try not to, but if you must you can use one of these on the floor without ICU team. 

DRUGDOSE AND ROUTEUSE FOR
Lido with epi Needle-site pain, especially if anticipate you will try multiple levels as the bottle in LP kits has a very small volume adequate for only one level. 

Order this and ask nurse to get it ready on every single patient but don't open unless needed
Fentanyl

25 mg IV for normal sized adult 

can go up to 50 mg IV for large people (>100kg)

If no access, same doses intranasally will work

 
Ativan (Lorazepam)0.5mg-1mg PO  or 0.5mg-1.0mg IV  
Ketamine0.3 mg/kg max of 35 mg over 15 minutes in an NS bagonly use if in the ICU; key is to push it slow to not cause laryngospasm! This rate is slow and likely will be ok on the floor. 

Drugs for MRI

MRI will frequently page you that a patient is freaking out/ in too much pain to sit still for an MRI.  

Return the call immediately and dose one of the following drugs. 

Remember rules for conscious sedation at PUH only allow you to dose 1 at a time w/o ICU presence and certainly with just an MRI nurse (see below).  

TIP: if you know a pt is likely to freak out or be in too much pain to stay still, order one of the drugs below PRN and specify in comments to use in MRI if needed (save yourself a page).

NOTE: when ordering any of these drugs which may depress respiration, there is no harm in playing it safe and just putting the patient on a cardiac monitor with pulse ox. This is something that can easily go into the scanner with the patient, no reason not to do it.  

DRUGDOSE AND ROUTEUSE FOR
Valium

5mg PO, 2.5mg IV 

Anxiety / Agitation / claustrophobia  
Dilaudid0.2mg IV (0.5 if large / non-opioid ideally, naive only if "<65")Pain 
Ativan

0.5mg-1mg PO  or 0.5mg-1.0mg IV 

Anxiety / Agitation / claustrophobia  
Zyprexa (olanzapine)

start w/ 2.5 P.O. if geriatric / small / TBI 

up 5.0mg ODT/IM if excessive agitation / large 

up to 10mg max

Agitation